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Product details
- Target protein: asparaginase like 1
- Target gene: ASRGL1
- Verified species reactivity: Human
- Interspecies information: Highest antigen sequence indentity to the following orthologs: MOUSE - ENSMUSG00000024654 (76%)RAT - ENSRNOG00000020202 (74%)
- Clonality: Polyclonal
- Isotype: IgG
- Host: Rabbit
- Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Material Safety Data Sheet - Purification method: Affinity purified using the PrEST antigen as affinity ligand
- Antigen sequence: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
- ARLTLFHIEQGKTVEEAADLSLGYMKSRVKGLGGLIVVSKTGDWVAKWTSTSMPWAAAKDGKLHFGIDPDDT
- Notes: Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Current lot
- Unit size: 100µl
- Current lot: 000025148
- Concentration: 0.2 mg/ml
Applications
- Immunohistochemistry (IHC) recommended conditions
- Dilution: 1:200 - 1:500
- Retrieval method: HIER pH6
- Western Blot (WB) recommended conditions
- Working concentration: 0.04-0.4 µg/ml
Validation
- Immunohistochemistry (IHC)Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues. Validation of protein expression in IHC by comparing independent antibodies targeting different epitopes of the protein. Validated against independent antibody Anti-ASRGL1 HPA029725 All IHC characterization data in 44 normal tissues and 20 cancers for HPA055572 on the Human Protein Atlas
- Western Blot (WB)Genetic validation in WB by siRNA knockdown. Recombinant expression validation in WB using target protein overexpression.
Target information
- Protein name: asparaginase like 1
- Gene name: ASRGL1
- Alternative gene names: ALP, ALP1, FLJ22316
- Ensembl: ENSG00000162174
- Entrez: 80150
- UniProt: Q7L266
Shipping and storage
- Shipping: Normally shipped at ambient temperatureStorage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
References (3)
- TDP-43 proteinopathy in ALS is triggered by loss of ASRGL1 and associated with HML-2 expressionNat Commun , 2024 May 16; 15:4163. Epub 2024 May 162024 May 16
- Increased expression of ASRGL1 in invasive ductal carcinoma and its association with estrogen-progesterone receptor status of tumorsAm J Transl Res , 2021 Jul 15; 13(7):7928-7934. Epub 2021 Jul 152021 Jul 15
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Researcher Contributions
Join the Explorer Program Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order. Read more...
Alternative antibodies
Corresponding antigens
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Learn how we validate our antibodies, how we secure their reproducibility, and why we apply enhanced validation. Our antibodies are validated in IHC, ICC-IF, and WB.