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HPA053457
sialic acid binding Ig-like lectin 1, sialoadhesin

Anti-SIGLEC1 Antibody

Polyclonal Antibody against HUMAN SIGLEC1

0.2 mg/ml
In Stock (10+)
Delivery time: Ready to Ship
312,0 EUR
Lowest price during the previous 30 days before discount: 297,0 EUR
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Immunohistochemical staining of human lung shows strong membranous positivity in macrophages.

Immunohistochemical staining of human lung shows strong membranous positivity in macrophages.

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Product details

  • Target protein: sialic acid binding Ig-like lectin 1, sialoadhesin
  • Target gene: SIGLEC1
  • Verified species reactivity: Human
  • Interspecies information: Highest antigen sequence indentity to the following orthologs: MOUSE - ENSMUSG00000027322 (72%)RAT - ENSRNOG00000021243 (68%)
  • Clonality: Polyclonal
  • Isotype: IgG
  • Host: Rabbit
  • Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
    Material Safety Data Sheet
  • Purification method: Affinity purified using the PrEST antigen as affinity ligand
  • Antigen sequence: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
  • CTAQNLLGSISTIGRLQVEGARVVAEPGLDVPEGAALNLSCRLLGGPGPVGNSTFAWFWNDRRLHAEPVPTLAFTHVARAQAGMYH
  • Notes: Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

Current lot

  • Unit size: 25µl
  • Current lot: 000039243
  • Concentration: 0.2 mg/ml

Applications

  • Immunohistochemistry (IHC) recommended conditions
    • Dilution: 1:200 - 1:500
    • Retrieval method: HIER pH6

Target information

  • Protein name: sialic acid binding Ig-like lectin 1, sialoadhesin
  • Gene name: SIGLEC1
  • Alternative gene names: CD169dJ1009E24.1FLJ00051FLJ00055FLJ00073FLJ32150sialoadhesinSIGLEC-1SN
  • Ensembl: ENSG00000088827
  • Entrez: 6614
  • UniProt: Q9BZZ2

Shipping and storage

  • Shipping: Normally shipped at ambient temperatureStorage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

References (3)

  • Siglec-1 Macrophages and the Contribution of IFN to the Development of Autoimmune Congenital Heart BlockClancy RM, Halushka M, Rasmussen SE, Lhakhang T, Chang M, Buyon JPJ Immunol , 2018 Dec 5; 202(1):48-55. Epub 2018 Dec 52018 Dec 5
  • Differences in the frequency of macrophage and T cell markers between focal and crescentic classes of anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritisKidder D, Bray SE, Fleming SJ Nephropathol , 2016 Dec 25; 6(2):97-102. Epub 2016 Dec 252016 Dec 25
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Researcher Contributions

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