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HPA022015
cerebellar degeneration-related protein 2-like

Anti-CDR2L Antibody

Polyclonal Antibody against HUMAN CDR2L

0.1 mg/ml
In Stock (10+)
Delivery time: Ready to Ship
4 570,0 kr
Lowest price during the previous 30 days before discount: 4 352,0 kr
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Immunohistochemistry analysis in human duodenum and skeletal muscle tissues using HPA022015 antibody. Corresponding CDR2L RNA-seq data are presented for the same tissues.

Immunohistochemistry analysis in human duodenum and skeletal muscle tissues using HPA022015 antibody. Corresponding CDR2L RNA-seq data are presented for the same tissues.

Product details

  • Target protein: cerebellar degeneration-related protein 2-like
  • Target gene: CDR2L
  • Verified species reactivity: Human, Mouse, Rat
  • Interspecies information: Highest antigen sequence indentity to the following orthologs: MOUSE - ENSMUSG00000050910 (93%)RAT - ENSRNOG00000025815 (94%)
  • Clonality: Polyclonal
  • Isotype: IgG
  • Host: Rabbit
  • Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
    Material Safety Data Sheet
  • Purification method: Affinity purified using the PrEST antigen as affinity ligand
  • Antigen sequence: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
  • DSSWRDLRGGEEGQGEVKAGEKSLSQHVEAVDKRLEQSQPEYKALFKEIFSRIQKTKADINATKVKTHSS
  • Notes: Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

Current lot

  • Unit size: 100µl
  • Current lot: C119366
  • Concentration: 0.1 mg/ml

Applications

  • Immunofluorescence in Cell Lines (ICC-IF) recommended conditions
    • Working concentration: 0.25-2 µg/ml
    • Fixation/Permeabilization: PFA/Triton X-100
  • Immunohistochemistry (IHC) recommended conditions
    • Dilution: 1:50 - 1:200
    • Retrieval method: HIER pH6
  • Western Blot (WB) recommended conditions
    • Working concentration: 0.04-0.4 µg/ml

Validation

Target information

  • Protein name: cerebellar degeneration-related protein 2-like
  • Gene name: CDR2L
  • Alternative gene names: HUMPPA
  • Ensembl: ENSG00000109089
  • Entrez: 30850
  • UniProt: Q86X02

Shipping and storage

  • Shipping: Normally shipped at ambient temperatureStorage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

References (5)

  • Paraneoplastic cerebellar degeneration: Yo antibody alters mitochondrial calcium buffering capacityPanja D, Vedeler CA, Schubert MNeuropathol Appl Neurobiol , 2018 May 24; 45(2):141-156. Epub 2018 May 242018 May 24
  • Cerebellar degeneration-related proteins 2 and 2-like are present in ovarian cancer in patients with and without Yo antibodiesRaspotnig M, Haugen M, Thorsteinsdottir M, Stefansson I, Salvesen HB, Storstein A, Vedeler CACancer Immunol Immunother , 2017 Jul 14; 66(11):1463-1471. Epub 2017 Jul 142017 Jul 14
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Researcher Contributions

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